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CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines

Nanoparticle vaccines based on H. pylori ferritin are increasingly used as a vaccine platform for many pathogens, including RSV, influenza, and SARS-CoV-2. They have been found to elicit enhanced, long-lived B cell responses. The basis for improved efficacy of ferritin nanoparticle vaccines remains...

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Detalles Bibliográficos
Autores principales: Nelson, Sean A., Richards, Katherine A., Glover, Maryah A., Chaves, Francisco A., Crank, Michelle C., Graham, Barney S., Kanekiyo, Masaru, Sant, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605951/
https://www.ncbi.nlm.nih.gov/pubmed/36289232
http://dx.doi.org/10.1038/s41541-022-00547-0