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Role of ferroptosis on tumor progression and immunotherapy

Ferroptosis is triggered by intracellular iron leading to accumulation of lipid peroxidation consequent promotion of cell death. Cancer cell exhibits ability to evade ferroptosis by activation of antioxidant signaling pathways such as SLC7A11/GPX4 axis. In addition to transcriptional regulation on f...

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Detalles Bibliográficos
Autores principales: Gong, Deting, Chen, Mingjun, Wang, Yuhan, Shi, Juanjuan, Hou, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605952/
https://www.ncbi.nlm.nih.gov/pubmed/36289191
http://dx.doi.org/10.1038/s41420-022-01218-8