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Cftr deletion in mouse epithelial and immune cells differentially influence the intestinal microbiota

Cystic fibrosis (CF) is a life-threatening genetic disorder, caused by mutations in the CF transmembrane-conductance regulator gene (cftr) that encodes CFTR, a cAMP-activated chloride and bicarbonate channel. Clinically, CF lung disease dominates the adult patient population. However, its gastrointe...

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Detalles Bibliográficos
Autores principales: Scull, Callie E., Luo, Meng, Jennings, Scott, Taylor, Christopher M., Wang, Guoshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605958/
https://www.ncbi.nlm.nih.gov/pubmed/36289287
http://dx.doi.org/10.1038/s42003-022-04101-5