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GABA(A) receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β

Gangliogliomas (GGs) are low-grade brain tumours that cause intractable focal epilepsy in children and adults. In GG, as in epileptogenic focal malformations (i.e., tuberous sclerosis complex, TSC), there is evidence of sustained neuroinflammation with involvement of the pro-inflammatory cytokine IL...

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Detalles Bibliográficos
Autores principales: Ruffolo, Gabriele, Alfano, Veronica, Romagnolo, Alessia, Zimmer, Till, Mills, James D., Cifelli, Pierangelo, Gaeta, Alessandro, Morano, Alessandra, Anink, Jasper, Mühlebner, Angelika, Vezzani, Annamaria, Aronica, Eleonora, Palma, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605959/
https://www.ncbi.nlm.nih.gov/pubmed/36289354
http://dx.doi.org/10.1038/s41598-022-22806-9