ACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway

Although tyrosine kinase inhibitors (TKIs) improve the prognosis of chronic myeloid leukemia (CML) patients, resistance to TKIs and residual leukemia stem cells (LSCs) inevitably become the bottleneck of cure. Therefore, we need to explore novel treatment strategies based on conventional treatment s...

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Detalles Bibliográficos
Autores principales: Liu, Wen, Zhu, Xiaoying, Tang, Ling, Shen, Na, Cheng, Fanjun, Zou, Ping, You, Yong, Yuan, Guolin, Li, Qing, Zhu, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606008/
https://www.ncbi.nlm.nih.gov/pubmed/36289272
http://dx.doi.org/10.1038/s41598-022-21009-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606008/
https://www.ncbi.nlm.nih.gov/pubmed/36289272
http://dx.doi.org/10.1038/s41598-022-21009-6

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