Cargando…

ACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway

Although tyrosine kinase inhibitors (TKIs) improve the prognosis of chronic myeloid leukemia (CML) patients, resistance to TKIs and residual leukemia stem cells (LSCs) inevitably become the bottleneck of cure. Therefore, we need to explore novel treatment strategies based on conventional treatment s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wen, Zhu, Xiaoying, Tang, Ling, Shen, Na, Cheng, Fanjun, Zou, Ping, You, Yong, Yuan, Guolin, Li, Qing, Zhu, Xiaojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606008/ https://www.ncbi.nlm.nih.gov/pubmed/36289272 http://dx.doi.org/10.1038/s41598-022-21009-6

Ejemplares similares

SIRT1 alleviates senescence of degenerative human intervertebral disc cartilage endo-plate cells via the p53/p21 pathway
por: Zhou, Nian, et al.
Publicado: (2016)

Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism
por: Xiang, Qun-yan, et al.
Publicado: (2020)

EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway
por: Endo, Akifumi, et al.
Publicado: (2016)

Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway
por: Zhang, Erli, et al.
Publicado: (2015)

p53 Gene (NY-CO-13) Levels in Patients with Chronic Myeloid Leukemia: The Role of Imatinib and Nilotinib
por: Al-kuraishy, Hayder M., et al.
Publicado: (2018)

Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
por: Tran, Duc, et al.
Publicado: (2014)

Hyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines
por: Lompardía, Silvina, et al.
Publicado: (2019)

Overexpression of P‐glycoprotein and resistance to Imatinib in chronic myeloid leukemia patients
por: Ammar, Mariam, et al.
Publicado: (2020)

Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines
por: Wang, Qian, et al.
Publicado: (2017)

Luteolin inhibits H(2)O(2)-induced cellular senescence via modulation of SIRT1 and p53
por: Zhu, Ri Zhe, et al.
Publicado: (2021)

Metoprolol Protects Against Arginine Vasopressin-Induced Cellular Senescence in H9C2 Cardiomyocytes by Regulating the Sirt1/p53/p21 Axis
por: Li, Qiang, et al.
Publicado: (2021)

Long-term outcomes of frontline imatinib therapy for chronic myeloid leukemia in China
por: Cheng, Fang, et al.
Publicado: (2023)

p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6
por: Phalke, Sameer, et al.
Publicado: (2012)

Knockdown of MBP-1 in Human Foreskin Fibroblasts Induces p53-p21 Dependent Senescence
por: Ghosh, Asish K., et al.
Publicado: (2008)

Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway
por: Wang, Guihua, et al.
Publicado: (2017)

Correction: Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway
por: Wang, Guihua, et al.
Publicado: (2021)

Author Correction: Hyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines
por: Lompardía, Silvina, et al.
Publicado: (2020)

Imatinib in Chronic Myeloid Leukemia: an Overview
por: Sacha, Tomasz
Publicado: (2014)

P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia
por: Cang, Shundong, et al.
Publicado: (2008)

Cooperation between p21 and Akt is required for p53‐dependent cellular senescence
por: Kim, Young Yeon, et al.
Publicado: (2017)

Tumor necrosis factor α knockout impaired tumorigenesis in chronic myeloid leukemia cells partly by metabolism modification and miRNA regulation
por: Shen, Na, et al.
Publicado: (2019)

P659: BUPARLISIB A PROMISING THERAPEUTIC APPROACH IN CHRONIC MYELOID LEUKEMIA RESISTANT TO IMATINIB
por: Alves, Raquel, et al.
Publicado: (2023)

Imatinib in chronic myeloid leukemia elderly patients
por: Gugliotta, Gabriele, et al.
Publicado: (2011)

sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis
por: Tan, Jiajia, et al.
Publicado: (2023)

Coexistence of P190 and P210 BCR/ABL transcripts in chronic myeloid leukemia blast crisis resistant to imatinib
por: Junmei, Zhao, et al.
Publicado: (2015)

ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
por: Yang, Yufei, et al.
Publicado: (2022)

A novel dic (17;18) (p13.1;q11.2) with loss of TP53 and BCR/ABL rearrangement in an Imatinib resistant chronic myeloid leukemia
por: Al-achkar, Walid, et al.
Publicado: (2012)

circ-Sirt1 Decelerates Senescence by Inhibiting p53 Activation in Vascular Smooth Muscle Cells, Ameliorating Neointima Formation
por: Kong, Peng, et al.
Publicado: (2021)

A novel t(3;12)(q21;p13) translocation in a patient with accelerated chronic myeloid leukemia after imatinib and nilotinib therapy
por: Bennour, Ayda, et al.
Publicado: (2013)

PIK3R3 inhibits cell senescence through p53/p21 signaling
por: Chen, Qianzhi, et al.
Publicado: (2020)

Black Ginseng Ameliorates Cellular Senescence via p53-p21/p16 Pathway in Aged Mice
por: Lee, Su-Jeong, et al.
Publicado: (2022)

RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC
por: Majumder, Mrinmoyee, et al.
Publicado: (2016)

Myeloid Neoplasms with t(5;12) and ETV6-ACSL6 Gene Fusion, Potential Mimickers of Myeloid Neoplasm with PDGFRB Rearrangement: Case Report with Imatinib Therapy and Review of the Literature
por: De Luca-Johnson, Javier, et al.
Publicado: (2016)

Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells
por: Morita, Ken, et al.
Publicado: (2017)

A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia
por: Hleihel, Rita, et al.
Publicado: (2021)

Reactive oxygen species and p21(Waf1/Cip1) are both essential for p53-mediated senescence of head and neck cancer cells
por: Fitzgerald, A L, et al.
Publicado: (2015)

Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia
por: Ramchandren, Radhakrishnan, et al.
Publicado: (2009)

Monitoring imatinib plasma concentrations in chronic myeloid leukemia
por: Martins, Darlize Hübner, et al.
Publicado: (2011)

Targeted treatment of chronic myeloid leukemia: role of imatinib
por: Tamascar, Ila, et al.
Publicado: (2009)

Therapy of Chronic Myeloid Leukemia: Twilight of the Imatinib Era?
por: Trela, Ewelina, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_90k9qsng75rkl2uu7m87q2vdvf