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X-ray multiscale 3D neuroimaging to quantify cellular aging and neurodegeneration postmortem in a model of Alzheimer’s disease

PURPOSE: Modern neuroimaging lacks the tools necessary for whole-brain, anatomically dense neuronal damage screening. An ideal approach would include unbiased histopathologic identification of aging and neurodegenerative disease. METHODS: We report the postmortem application of multiscale X-ray phas...

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Detalles Bibliográficos
Autores principales: Barbone, Giacomo E., Bravin, Alberto, Mittone, Alberto, Pacureanu, Alexandra, Mascio, Giada, Di Pietro, Paola, Kraiger, Markus J., Eckermann, Marina, Romano, Mariele, Hrabě de Angelis, Martin, Cloetens, Peter, Bruno, Valeria, Battaglia, Giuseppe, Coan, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606093/
https://www.ncbi.nlm.nih.gov/pubmed/35852558
http://dx.doi.org/10.1007/s00259-022-05896-5