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X-ray multiscale 3D neuroimaging to quantify cellular aging and neurodegeneration postmortem in a model of Alzheimer’s disease
PURPOSE: Modern neuroimaging lacks the tools necessary for whole-brain, anatomically dense neuronal damage screening. An ideal approach would include unbiased histopathologic identification of aging and neurodegenerative disease. METHODS: We report the postmortem application of multiscale X-ray phas...
Autores principales: | Barbone, Giacomo E., Bravin, Alberto, Mittone, Alberto, Pacureanu, Alexandra, Mascio, Giada, Di Pietro, Paola, Kraiger, Markus J., Eckermann, Marina, Romano, Mariele, Hrabě de Angelis, Martin, Cloetens, Peter, Bruno, Valeria, Battaglia, Giuseppe, Coan, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606093/ https://www.ncbi.nlm.nih.gov/pubmed/35852558 http://dx.doi.org/10.1007/s00259-022-05896-5 |
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