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Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA

Immunoglobulin A (IgA) is a candidate antibody for oral passive immunization against mucosal pathogens like Shiga toxin-producing Escherichia coli (STEC). We previously established a mouse IgG monoclonal antibody (mAb) neutralizing Shiga toxin 1 (Stx1), a bacterial toxin secreted by STEC. We designe...

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Detalles Bibliográficos
Autores principales: Nakanishi, Katsuhiro, Takase, Taichi, Ohira, Yuya, Ida, Ryota, Mogi, Noriko, Kikuchi, Yuki, Matsuda, Minami, Kurohane, Kohta, Akimoto, Yoshihiro, Hayakawa, Junri, Kawakami, Hayato, Niwa, Yasuo, Kobayashi, Hirokazu, Umemoto, Eiji, Imai, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606113/
https://www.ncbi.nlm.nih.gov/pubmed/36289440
http://dx.doi.org/10.1038/s41598-022-22851-4