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Dual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury

Despite the effort on developing new treatments, therapy for neuropathic pain is still a clinical challenge and combination therapy regimes of two or more drugs are often needed to improve efficacy. Accumulating evidence shows an altered expression and activity of histone acetylation enzymes in chro...

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Detalles Bibliográficos
Autores principales: Borgonetti, Vittoria, Meacci, Elisabetta, Pierucci, Federica, Romanelli, Maria Novella, Galeotti, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606187/
https://www.ncbi.nlm.nih.gov/pubmed/35501470
http://dx.doi.org/10.1007/s13311-022-01243-6