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Pridopidine Promotes Synaptogenesis and Reduces Spatial Memory Deficits in the Alzheimer’s Disease APP/PS1 Mouse Model

Sigma-1 receptor agonists have recently gained a great deal of interest due to their anti-amnesic, neuroprotective, and neurorestorative properties. Compounds such as PRE-084 or pridopidine (ACR16) are being studied as a potential treatment against cognitive decline associated with neurodegenerative...

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Detalles Bibliográficos
Autores principales: Estévez-Silva, Héctor M., Cuesto, Germán, Romero, Ninovska, Brito-Armas, José Miguel, Acevedo-Arozena, Abraham, Acebes, Ángel, Marcellino, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606189/
https://www.ncbi.nlm.nih.gov/pubmed/35917088
http://dx.doi.org/10.1007/s13311-022-01280-1