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Pridopidine Promotes Synaptogenesis and Reduces Spatial Memory Deficits in the Alzheimer’s Disease APP/PS1 Mouse Model
Sigma-1 receptor agonists have recently gained a great deal of interest due to their anti-amnesic, neuroprotective, and neurorestorative properties. Compounds such as PRE-084 or pridopidine (ACR16) are being studied as a potential treatment against cognitive decline associated with neurodegenerative...
Autores principales: | Estévez-Silva, Héctor M., Cuesto, Germán, Romero, Ninovska, Brito-Armas, José Miguel, Acevedo-Arozena, Abraham, Acebes, Ángel, Marcellino, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606189/ https://www.ncbi.nlm.nih.gov/pubmed/35917088 http://dx.doi.org/10.1007/s13311-022-01280-1 |
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