Therapeutic effects of Fc gamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita

Epidermolysis bullosa acquisita (EBA) is a subepidermal autoimmune bullous disease caused by autoantibodies targeting type VII collagen (COL7). It is characterized by inflammation and subepidermal blistering mainly through immune complex (IC)-mediated activation of neutrophils. In experimental EBA,...

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Detalles Bibliográficos
Autores principales: Haeger, Swantje C., Kridin, Khalaf, Pieper, Mario, Griewahn, Laura, Nimmerjahn, Falk, Zillikens, Detlef, König, Peter, Ludwig, Ralf J., Hundt, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606225/
https://www.ncbi.nlm.nih.gov/pubmed/36311755
http://dx.doi.org/10.3389/fimmu.2022.938306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606225/
https://www.ncbi.nlm.nih.gov/pubmed/36311755
http://dx.doi.org/10.3389/fimmu.2022.938306

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