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Complement-targeted therapies in kidney transplantation—insights from preclinical studies

Aberrant activation of the complement system contributes to solid-organ graft dysfunction and failure. In kidney transplantation, the complement system is implicated in the pathogenesis of antibody- and cell-mediated rejection, ischemia-reperfusion injury, and vascular injury. This has led to the ev...

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Detalles Bibliográficos
Autores principales: Anwar, Imran J., DeLaura, Isabel, Ladowski, Joseph, Gao, Qimeng, Knechtle, Stuart J., Kwun, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606228/
https://www.ncbi.nlm.nih.gov/pubmed/36311730
http://dx.doi.org/10.3389/fimmu.2022.984090