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Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples

The enzyme cytochrome P450 2D6 (CYP2D6) metabolises approximately 25% of commonly prescribed drugs, including analgesics, anti-hypertensives, and anti-depressants, among many others. Genetic variation in drug metabolising genes can alter how an individual responds to prescribed drugs, including pred...

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Detalles Bibliográficos
Autores principales: Hitchman, Leonie M., Faatoese, Allamanda, Merriman, Tony R., Miller, Allison L., Liau, Yusmiati, Graham, Oscar E. E., Kee, Ping Siu, Pearson, John F., Fakahau, Tony, Cameron, Vicky A., Kennedy, Martin A., Maggo, Simran D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606245/
https://www.ncbi.nlm.nih.gov/pubmed/36313436
http://dx.doi.org/10.3389/fgene.2022.1016416