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A fungal NRPS-PKS enzyme catalyses the formation of the flavonoid naringenin

Biosynthesis of the flavonoid naringenin in plants and bacteria is commonly catalysed by a type III polyketide synthase (PKS) using one p-coumaroyl-CoA and three malonyl-CoA molecules as substrates. Here, we report a fungal non-ribosomal peptide synthetase -polyketide synthase (NRPS-PKS) hybrid FnsA...

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Detalles Bibliográficos
Autores principales: Zhang, Hongjiao, Li, Zixin, Zhou, Shuang, Li, Shu-Ming, Ran, Huomiao, Song, Zili, Yu, Tao, Yin, Wen-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606254/
https://www.ncbi.nlm.nih.gov/pubmed/36289208
http://dx.doi.org/10.1038/s41467-022-34150-7