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Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor

G protein-coupled receptors (GPCRs) are important drug targets that mediate various signaling pathways by activating G proteins and engaging β-arrestin proteins. Despite its importance for the development of therapeutics with fewer side effects, the underlying mechanism that controls the balance bet...

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Detalles Bibliográficos
Autores principales: Liu, Junke, Tang, Hengmin, Xu, Chanjuan, Zhou, Shengnan, Zhu, Xunying, Li, Yuanyuan, Prézeau, Laurent, Xu, Tao, Pin, Jean-Philippe, Rondard, Philippe, Ji, Wei, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606269/
https://www.ncbi.nlm.nih.gov/pubmed/36289206
http://dx.doi.org/10.1038/s41467-022-34056-4