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Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor
G protein-coupled receptors (GPCRs) are important drug targets that mediate various signaling pathways by activating G proteins and engaging β-arrestin proteins. Despite its importance for the development of therapeutics with fewer side effects, the underlying mechanism that controls the balance bet...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606269/ https://www.ncbi.nlm.nih.gov/pubmed/36289206 http://dx.doi.org/10.1038/s41467-022-34056-4 |