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miR-4653-3p overexpression is associated with a poor prognosis of pancreatic ductal adenocarcinoma via HIPK2 downregulation

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignant tumor. Several upregulated and downregulated microRNAs (miRNAs) are associated with invasiveness, tumorigenesis, and prognosis of PDAC. Herein, using in situ hybridization, we evaluated miR-4653-3p expression and pancreatic intraepithelia...

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Detalles Bibliográficos
Autores principales: Hirabayashi, Kenichi, Miyazawa, Masaki, Takanashi, Yumi, Morimachi, Masashi, Kawanishi, Aya, Saika, Tsubasa, Nakagohri, Toshio, Nakamura, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606280/
https://www.ncbi.nlm.nih.gov/pubmed/36289359
http://dx.doi.org/10.1038/s41598-022-22950-2