Cargando…
Branched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming
Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, we h...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606345/ https://www.ncbi.nlm.nih.gov/pubmed/36311795 http://dx.doi.org/10.3389/fimmu.2022.966158 |