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Expression level of the reprogramming factor NeuroD1 is critical for neuronal conversion efficiency from different cell types

Several transcription factors, including NeuroD1, have been shown to act as neuronal reprogramming factors (RFs) that induce neuronal conversion from somatic cells. However, it remains unexplored whether expression levels of RFs in the original cells affect reprogramming efficiency. Here, we show th...

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Detalles Bibliográficos
Autores principales: Matsuda-Ito, Kanae, Matsuda, Taito, Nakashima, Kinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606360/
https://www.ncbi.nlm.nih.gov/pubmed/36289433
http://dx.doi.org/10.1038/s41598-022-22802-z