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Integrating machine learning with electronic health record data to facilitate detection of prolactin level and pharmacovigilance signals in olanzapine-treated patients

BACKGROUND AND AIM: Available evidence suggests elevated serum prolactin (PRL) levels in olanzapine (OLZ)-treated patients with schizophrenia. However, machine learning (ML)-based comprehensive evaluations of the influence of pathophysiological and pharmacological factors on PRL levels in OLZ-treate...

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Detalles Bibliográficos
Autores principales: Zhu, Xiuqing, Hu, Jinqing, Xiao, Tao, Huang, Shanqing, Shang, Dewei, Wen, Yuguan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606398/
https://www.ncbi.nlm.nih.gov/pubmed/36313772
http://dx.doi.org/10.3389/fendo.2022.1011492