The CRTh2 polymorphism rs533116 G > A associates with asthma severity in older females

BACKGROUND: CRTh2 is G protein coupled receptor for prostaglandin D2 (PGD)(2) expressed by immune cells that drive type 2 inflammation such as CD4(+) T cells (Th2), eosinophils and group 2 innate lymphoid cells (ILC2) as well as structural cells including smooth muscle and epithelium. CRTh2-expressi...

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Detalles Bibliográficos
Autores principales: Shrestha Palikhe, Nami, Mackenzie, Constance A., Licskai, Christopher, Kim, Richard B., Vliagoftis, Harissios, Cameron, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606418/
https://www.ncbi.nlm.nih.gov/pubmed/36314028
http://dx.doi.org/10.3389/fmed.2022.970495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606418/
https://www.ncbi.nlm.nih.gov/pubmed/36314028
http://dx.doi.org/10.3389/fmed.2022.970495

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