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The CRTh2 polymorphism rs533116 G > A associates with asthma severity in older females
BACKGROUND: CRTh2 is G protein coupled receptor for prostaglandin D2 (PGD)(2) expressed by immune cells that drive type 2 inflammation such as CD4(+) T cells (Th2), eosinophils and group 2 innate lymphoid cells (ILC2) as well as structural cells including smooth muscle and epithelium. CRTh2-expressi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606418/ https://www.ncbi.nlm.nih.gov/pubmed/36314028 http://dx.doi.org/10.3389/fmed.2022.970495 |