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Lack of placental neurosteroid alters cortical development and female somatosensory function

Placental endocrine function is essential to fetal brain development. Placental hormones include neurosteroids such as allopregnanolone (ALLO), a regulator of neurodevelopmental processes via positive allosteric modulation of the GABA(A) receptor (GABA(A)-R). Using a mouse model (plKO) in which the...

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Detalles Bibliográficos
Autores principales: Bakalar, Dana, O’Reilly, Jiaqi J., Lacaille, Helene, Salzbank, Jacquelyn, Ellegood, Jacob, Lerch, Jason P., Sasaki, Toru, Imamura, Yuka, Hashimoto-Torii, Kazue, Vacher, Claire-Marie, Penn, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606442/
https://www.ncbi.nlm.nih.gov/pubmed/36313771
http://dx.doi.org/10.3389/fendo.2022.972033