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Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus

OBJECTIVES: Premature cardiovascular events in systemic lupus erythematosus (SLE) contribute to morbidity and mortality, with no effective preventive strategies described to date. Immune dysregulation and metabolic disturbances appear to play prominent roles in the induction of vascular disease in S...

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Detalles Bibliográficos
Autores principales: Hasni, Sarfaraz, Temesgen-Oyelakin, Yenealem, Davis, Michael, Chu, Jun, Poncio, Elaine, Naqi, Mohammad, Gupta, Sarthak, Wang, Xinghao, Oliveira, Christopher, Claybaugh, Dillon, Dey, Amit, Lu, Shajia, Carlucci, Philip, Purmalek, Monica, Manna, Zerai G, Shi, Yinghui, Ochoa-Navas, Isabel, Chen, Jinguo, Mukherjee, Amrita, Han, Kyu Lee, Cheung, Foo, Koroleva, Galina, Belkaid, Yasmine, Tsang, John S, Apps, Richard, Thomas, Donald E, Heller, Theo, Gadina, Massimo, Playford, Martin P, Li, Xiaobai, Mehta, Nehal N, Kaplan, Mariana J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606512/
https://www.ncbi.nlm.nih.gov/pubmed/35914929
http://dx.doi.org/10.1136/ard-2022-222658