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PAX6 is frequently expressed in ependymal tumours and associated with prognostic relevant subgroups

AIMS: An ependymoma shows divergent morphological and molecular features depending on their location. The paired box 6 (PAX6) transcription factor is a putative tumour suppressor and drives cancer cells towards a stem cell-like state. A transcriptome study reported high PAX6 expression in ependymal...

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Detalles Bibliográficos
Autores principales: Tabasaran, Julian, Schuhmann, Martin, Ebinger, Martin, Honegger, Jürgen, Renovanz, Mirjam, Schittenhelm, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606524/
https://www.ncbi.nlm.nih.gov/pubmed/34183436
http://dx.doi.org/10.1136/jclinpath-2021-207526