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PAX6 is frequently expressed in ependymal tumours and associated with prognostic relevant subgroups
AIMS: An ependymoma shows divergent morphological and molecular features depending on their location. The paired box 6 (PAX6) transcription factor is a putative tumour suppressor and drives cancer cells towards a stem cell-like state. A transcriptome study reported high PAX6 expression in ependymal...
Autores principales: | Tabasaran, Julian, Schuhmann, Martin, Ebinger, Martin, Honegger, Jürgen, Renovanz, Mirjam, Schittenhelm, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606524/ https://www.ncbi.nlm.nih.gov/pubmed/34183436 http://dx.doi.org/10.1136/jclinpath-2021-207526 |
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