Human MHC class I molecule, HLA-A2.1, mediates activation of CD8(+) T cell IFN-γ production and the T cell-dependent protection against reactivation of cerebral Toxoplasma infection

To examine whether the HLA-A2.1, one of the most common MHC class I molecules in humans, activates the protective immunity against reactivation of cerebral infection with Toxoplasma gondii, HLA-A2.1-transgenic and wild-type (WT) mice were infected and treated with sulfadiazine to establish chronic i...

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Detalles Bibliográficos
Autores principales: Mani, Rajesh, Abdelaziz, Mohamed H., Michelon, Alexandra, Suzuki, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606666/
https://www.ncbi.nlm.nih.gov/pubmed/36311799
http://dx.doi.org/10.3389/fimmu.2022.1005059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606666/
https://www.ncbi.nlm.nih.gov/pubmed/36311799
http://dx.doi.org/10.3389/fimmu.2022.1005059

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