Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35

The inflammasome has been linked to diverse inflammatory and metabolic diseases, and tight control of inflammasome activation is necessary to avoid excessive inflammation. Kynurenic acid (KA) is a tryptophan metabolite in the kynurenine pathway. However, the roles and mechanisms of the regulation of...

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Detalles Bibliográficos
Autores principales: Sun, Tianyin, Xie, Ruiqian, He, Hongbin, Xie, Qianqian, Zhao, Xueqin, Kang, Guijie, Cheng, Chen, Yin, Wenwei, Cong, Jingjing, Li, Jing, Wang, Xuefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606686/
https://www.ncbi.nlm.nih.gov/pubmed/36311752
http://dx.doi.org/10.3389/fimmu.2022.1019365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606686/
https://www.ncbi.nlm.nih.gov/pubmed/36311752
http://dx.doi.org/10.3389/fimmu.2022.1019365

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