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Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35
The inflammasome has been linked to diverse inflammatory and metabolic diseases, and tight control of inflammasome activation is necessary to avoid excessive inflammation. Kynurenic acid (KA) is a tryptophan metabolite in the kynurenine pathway. However, the roles and mechanisms of the regulation of...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606686/ https://www.ncbi.nlm.nih.gov/pubmed/36311752 http://dx.doi.org/10.3389/fimmu.2022.1019365 |