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Monomethyl lithospermate alleviates ischemic stroke injury in middle cerebral artery occlusion mice in vivo and protects oxygen glucose deprivation/reoxygenation induced SHSY-5Y cells in vitro via activation of PI3K/Akt signaling

Stroke is a fatal neurological disease, which seriously threatens human health and life. Ischemic stroke (IS) is the most common type of stroke in clinic. Its pathogenesis is very complex, mainly caused by nerve damage caused by brain blood supply disorder. Previous studies have confirmed that natur...

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Detalles Bibliográficos
Autores principales: Yang, Fang, Chen, Ze-Ran, Yang, Xu-Hong, Xu, Yue, Ran, Ning-Jing, Liu, Mei-Jun, Jin, Shuo-Guo, Jia, Hua-Nan, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606694/
https://www.ncbi.nlm.nih.gov/pubmed/36313310
http://dx.doi.org/10.3389/fphar.2022.1024439