CDK2 regulates aminoglycoside-induced hair cell death through modulating c-Jun activity: Inhibiting CDK2 to preserve hearing

Sensory hair cell death caused by the ototoxic side effects of many clinically used drugs leads to permanent sensorineural hearing loss in patients. Aminoglycoside antibiotics are widely used and well-known for their ototoxicity, but the molecular mechanisms of aminoglycoside-induced hair cell death...

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Detalles Bibliográficos
Autores principales: Tao, Litao, Segil, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606710/
https://www.ncbi.nlm.nih.gov/pubmed/36311033
http://dx.doi.org/10.3389/fnmol.2022.1013383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606710/
https://www.ncbi.nlm.nih.gov/pubmed/36311033
http://dx.doi.org/10.3389/fnmol.2022.1013383

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