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Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells

A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated in human colon adenocarcinoma cells (SW480 and SW620) and non-malignant cell lines (HaCaT and CHO-K1). Hybrid 4a displaye...

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Detalles Bibliográficos
Autores principales: Moreno-Quintero, Gustavo, Castrillón-Lopez, Wilson, Herrera-Ramirez, Angie, Yepes-Pérez, Andrés F., Quintero-Saumeth, Jorge, Cardona-Galeano, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606943/
https://www.ncbi.nlm.nih.gov/pubmed/36297411
http://dx.doi.org/10.3390/ph15101299