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Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging

To develop novel radiolabeled amino acid tumor imaging agents, 4-methoxy-(L)-phenylalanine dithiocarbamate (MOPADTC) was synthesized successfully, and two kinds of (99m)Tc-labeled complexes ([(99m)Tc]TcN-MOPADTC and [(99m)Tc]TcO-MOPADTC) with high radiochemical purities (RCP > 95%) were obtained....

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Detalles Bibliográficos
Autores principales: Yin, Guangxing, Ruan, Qing, Jiang, Yuhao, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607073/
https://www.ncbi.nlm.nih.gov/pubmed/36297631
http://dx.doi.org/10.3390/pharmaceutics14102196