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Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging
To develop novel radiolabeled amino acid tumor imaging agents, 4-methoxy-(L)-phenylalanine dithiocarbamate (MOPADTC) was synthesized successfully, and two kinds of (99m)Tc-labeled complexes ([(99m)Tc]TcN-MOPADTC and [(99m)Tc]TcO-MOPADTC) with high radiochemical purities (RCP > 95%) were obtained....
Autores principales: | Yin, Guangxing, Ruan, Qing, Jiang, Yuhao, Zhang, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607073/ https://www.ncbi.nlm.nih.gov/pubmed/36297631 http://dx.doi.org/10.3390/pharmaceutics14102196 |
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