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Switching the N-Capping Region from all-L to all-D Amino Acids in a VEGF Mimetic Helical Peptide

The N-capping region of an α-helix is a short N-terminal amino acid stretch that contributes to nucleate and stabilize the helical structure. In the VEGF mimetic helical peptide QK, the N-capping region was previously demonstrated to be a key factor of QK helical folding. In this paper, we explored...

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Detalles Bibliográficos
Autores principales: De Rosa, Lucia, Diana, Donatella, Capasso, Domenica, Stefania, Rachele, Di Stasi, Rossella, Fattorusso, Roberto, D’Andrea, Luca Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607104/
https://www.ncbi.nlm.nih.gov/pubmed/36296575
http://dx.doi.org/10.3390/molecules27206982