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High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening

How to rapidly and accurately screen bioactive components from complex natural products remains a major challenge. In this study, a screening platform for pancreatic lipase (PL) inhibitors was established by combining magnetic beads-based ligand fishing and high-resolution bioassay profiling. This p...

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Detalles Bibliográficos
Autores principales: Jian, Jingyi, Yuan, Jiaming, Fan, Yu, Wang, Jincai, Zhang, Tingting, Kool, Jeroen, Jiang, Zhengjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607159/
https://www.ncbi.nlm.nih.gov/pubmed/36296516
http://dx.doi.org/10.3390/molecules27206923