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Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment

The aims of this study are (i) to develop a population pharmacokinetic/pharmacodynamic model of daptomycin in patients with normal and impaired renal function, and (ii) to establish the optimal dose recommendation of daptomycin in clinical practice. Several structural PK models including linear and...

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Detalles Bibliográficos
Autores principales: García-Martínez, Teresa, Bellés-Medall, María Dolores, García-Cremades, Maria, Ferrando-Piqueres, Raúl, Mangas-Sanjuán, Victor, Merino-Sanjuan, Matilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607246/
https://www.ncbi.nlm.nih.gov/pubmed/36297661
http://dx.doi.org/10.3390/pharmaceutics14102226