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The Hydrolysis Rate of Paraoxonase-1 Q and R Isoenzymes: An In Silico Study Based on In Vitro Data

Human serum paraoxonase-1 (PON1) is an important hydrolase-type enzyme found in numerous tissues. Notably, it can exist in two isozyme-forms, Q and R, that exhibit different activities. This study presents an in silico (QSAR, Docking, MD and QM/MM) study of a set of compounds on the activity towards...

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Detalles Bibliográficos
Autores principales:	Karabulut, Sedat, Mansour, Basel, Casanola-Martin, Gerardo M., Rasulev, Bakhtiyor, Gauld, James W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607273/ https://www.ncbi.nlm.nih.gov/pubmed/36296373 http://dx.doi.org/10.3390/molecules27206780

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