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Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties

2,6-dipeptidyl-anthraquinones are polycyclic planar systems substituted at opposite ring positions by short aminoacyl side chains. Derivatives with positively charged terminal amino acids showed in vitro inhibition of HIV-1 nucleocapsid (NC) protein correlating with threading intercalation through n...

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Detalles Bibliográficos
Autores principales: Sosic, Alice, Frecentese, Francesco, Olivato, Giulia, Rollo, Daniele, Carraro, Caterina, Gamba, Elia, Santagada, Vincenzo, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607300/
https://www.ncbi.nlm.nih.gov/pubmed/36298688
http://dx.doi.org/10.3390/v14102133