Synthesis, Conformational Analysis and Evaluation of the 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thiazepines as Potential α-Glucosidase and/or α-Amylase Inhibitors

The ambident electrophilic character of the 5-bromo-2-hydroxychalcones and the binucleophilic nature of 2-aminothiophenol were exploited to construct the 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thiazepines. The structures and conformation of these 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thia...

Descripción completa

Detalles Bibliográficos
Autores principales: Nkoana, Jackson K., Maluleka, Marole M., Mphahlele, Malose J., Mampa, Richard M., Choong, Yee Siew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607343/
https://www.ncbi.nlm.nih.gov/pubmed/36296528
http://dx.doi.org/10.3390/molecules27206935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607343/
https://www.ncbi.nlm.nih.gov/pubmed/36296528
http://dx.doi.org/10.3390/molecules27206935

Ejemplares similares