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Combined In Silico and In Vitro Evidence Supporting an Aurora A Kinase Inhibitory Role of the Anti-Viral Drug Rilpivirine and an Anti-Proliferative Influence on Cancer Cells

The global burden of cancer necessitates rapid and ongoing development of effective cancer therapies. One promising approach in this context is the repurposing of existing non-cancer drugs for cancer indications. A key to this approach is selecting the cellular targets against which to identify nove...

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Detalles Bibliográficos
Autores principales: Islam, Saiful, Teo, Theodosia, Kumarasiri, Malika, Slater, Martin, Martin, Jennifer H., Wang, Shudong, Head, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607353/
https://www.ncbi.nlm.nih.gov/pubmed/36297298
http://dx.doi.org/10.3390/ph15101186