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Current In Vitro and In Vivo Models to Study MCPyV-Associated MCC

Merkel cell polyomavirus (MCPyV) is the only human polyomavirus currently known to cause human cancer. MCPyV is believed to be an etiological factor in at least 80% of cases of the rare but aggressive skin malignancy Merkel cell carcinoma (MCC). In these MCPyV+ MCC tumors, clonal integration of the...

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Detalles Bibliográficos
Autores principales: Loke, Amanda S. W., Lambert, Paul F., Spurgeon, Megan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607385/
https://www.ncbi.nlm.nih.gov/pubmed/36298759
http://dx.doi.org/10.3390/v14102204