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Non-Cryoprecipitation Separation of Coagulation FVIII and Prothrombin Complex Proteins by Pseudoaffinity Calcium Elution Chromatography Using Anion Exchange Resin

Hemophilia A is treated with human plasma coagulation factor VIII (FVIII) replacement therapy and Hemophilia B with coagulation factor IX, which is purified from prothrombin complex concentrate (PCC). In this paper we evaluated the separation of FVIII and PCC by directly loading raw thawed plasma to...

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Detalles Bibliográficos
Autores principales: Feliciano, Gabriel Pinna, Arimori, Sara Hayama, Nakao, Vinicius Watanabe, Dos Santos, Joice Rodrigues, Martins, Elizabeth A. L., Bemquerer, Marcelo Porto, Cheng, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607535/
https://www.ncbi.nlm.nih.gov/pubmed/36297304
http://dx.doi.org/10.3390/ph15101192