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Non-Cryoprecipitation Separation of Coagulation FVIII and Prothrombin Complex Proteins by Pseudoaffinity Calcium Elution Chromatography Using Anion Exchange Resin
Hemophilia A is treated with human plasma coagulation factor VIII (FVIII) replacement therapy and Hemophilia B with coagulation factor IX, which is purified from prothrombin complex concentrate (PCC). In this paper we evaluated the separation of FVIII and PCC by directly loading raw thawed plasma to...
Autores principales: | Feliciano, Gabriel Pinna, Arimori, Sara Hayama, Nakao, Vinicius Watanabe, Dos Santos, Joice Rodrigues, Martins, Elizabeth A. L., Bemquerer, Marcelo Porto, Cheng, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607535/ https://www.ncbi.nlm.nih.gov/pubmed/36297304 http://dx.doi.org/10.3390/ph15101192 |
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