Cargando…

Novel Chelating Agents for Zirconium-89-Positron Emission Tomography (PET) Imaging: Synthesis, DFT Calculation, Radiolabeling, and In Vitro and In Vivo Complex Stability

[Image: see text] We report the synthesis and evaluation of novel chelating agents for zirconium-89 ((89)Zr) with positron emission tomography (PET) imaging applications. New chelating agents NODHA, NOTHA, and NODHA-PY were constructed on 1,4,7-triazacyclononane (TACN) and possess hydroxamic acid or...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Chi Soo, Zhang, Shuyuan, Wang, Haixing, Liu, Yujie, Ren, Siyuan, Chen, Yanda, Li, Jingbai, Bandara, Nilantha, Rogachev, Andrey Yu, Rogers, Buck E., Chong, Hyun-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607665/
https://www.ncbi.nlm.nih.gov/pubmed/36312419
http://dx.doi.org/10.1021/acsomega.2c03478