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Synthesis and Characterization of Functionalized Amino Dihydropyrimidines Toward the Analysis of their Antibacterial Structure–Activity Relationships and Mechanism of Action

[Image: see text] Antibiotic resistance among bacteria puts immense strain on public health. The discovery of new antibiotics that work through unique mechanisms is one important pillar toward combating this threat of resistance. A functionalized amino dihydropyrimidine was reported to exhibit antib...

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Detalles Bibliográficos
Autores principales: Boyer, Zachary W., Kessler, Hannah, Brosman, Hannah, Ruud, Kirsten J., Falkowski, Alan F., Viollet, Constance, Bourne, Christina R., O’Reilly, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607683/
https://www.ncbi.nlm.nih.gov/pubmed/36312355
http://dx.doi.org/10.1021/acsomega.2c05071