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Development and Qualification of an Antigen Integrity Assay for a Plasmodium falciparum Malaria Transmission Blocking Vaccine Candidate, Pfs230

During development of a subunit vaccine, monitoring integrity of the recombinant protein for process development and quality control is critical. Pfs230 is a leading malaria transmission blocking vaccine candidate and the first to reach a Phase 2 clinical trial. The Pfs230 protein is expressed on th...

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Detalles Bibliográficos
Autores principales: Miura, Kazutoyo, Pham, Thao P., Lee, Shwu-Maan, Plieskatt, Jordan, Diouf, Ababacar, Sagara, Issaka, Coelho, Camila H., Duffy, Patrick E., Wu, Yimin, Long, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607959/
https://www.ncbi.nlm.nih.gov/pubmed/36298492
http://dx.doi.org/10.3390/vaccines10101628