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Prognostic Role of DNA Damage Response Genes Mutations and their Association With the Sensitivity of Olaparib in Prostate Cancer Patients

OBJECTIVE: Evidence shows that gene mutation is a significant proportion of genetic factors associated with prostate cancer. The DNA damage response (DDR) is a signal cascade network that aims to maintain genomic integrity in cells. This comprehensive study was performed to determine the link betwee...

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Detalles Bibliográficos
Autores principales: Zhang, Dong, Xu, Xinchi, Wei, Yuang, Chen, Xinglin, Li, Guangyao, Lu, Zhongwen, Zhang, Xu, Ren, Xiaohan, Wang, Shangqian, Qin, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608002/
https://www.ncbi.nlm.nih.gov/pubmed/36283420
http://dx.doi.org/10.1177/10732748221129451