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Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis
The innate immune DNA sensing cGAS-STING signaling pathway has been widely recognized for inducing interferons (IFNs) and subsequent antiviral state. In addition to IFN, the cGAS-STING pathway also elicits other cell autonomous immunity events including autophagy and apoptosis. However, the downstre...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608012/ https://www.ncbi.nlm.nih.gov/pubmed/36311807 http://dx.doi.org/10.3389/fimmu.2022.1021384 |